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Symbol
Name
ID

Dlx5
distal-less homeobox 5
MGI:101926

Phenotype annotations related to nervous system

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Intellectual disability
Disease(s) Associated with DLX5	Intellectual disability
split hand-foot malformation 1

Mouse Phenotypes

abnormal axon extension

absent vomeronasal organ

small vomeronasal organ

open neural tube

abnormal brain development

abnormal rostral migratory stream morphology

abnormal olfactory bulb morphology

abnormal olfactory bulb granule cell morphology

abnormal olfactory bulb periglomerular cell morphology

abnormal mitral cell morphology

small olfactory bulb

abnormal sensory neuron innervation pattern

anencephaly

exencephaly

abnormal GABAergic neuron morphology

small trigeminal ganglion

abnormal olfactory nerve morphology

Availability

Mouse Genotype

Dlx5/Dlx6^tm1Levi/Dlx5/Dlx6^tm1Levi

Dlx5^tm1Jlr/Dlx5^tm1Jlr

Dlx5^tm1Levi/Dlx5^tm1Levi

Dlx5^tm1Jlr/Dlx5⁺

!

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23